Direction of Replication in growing strand formed on the upper strand 3' <-------------------------------------------------------------- 5'

5' PO₄ ------ A T T C C CG T A T C T G --------OH 3'

3' OH ------ T A A G G GC A T A G A C --------PO₄ 5

Direction of Replication in growing strand formed on the lower strand 5' ----------------------------------------------------------------->3'

In both strands replication moves from the 5' to the 3' end in the growing strand. Because the strands are antiparallel replication proceeds in the opposite direction in the two strands.