Biology 113
Fall 2001
Lecture outline 3
8/31/01
The macromolecular origin of life
So, what needs to be explained?
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Where did the first organic molecules come from?
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How did they form into polymers?
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How did they begin replicating? What were the first replicators?
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Where did they get the energy for all of this?
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How did they become isolated from everything else?
Where did the first organic molecules come from?
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The Stanley Miller experiment
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The chirality of biochemical molecules.
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The exobiotic hypothesis
How did monomers form into polymers?
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Polymers form by condensation reactions
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Breakdown of polymers is by hydrolysis
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Problem of non-specific polymerization
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