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DNA Replication
Meselson and Stahl: DNA replicates semiconservatively
from Freeman's Biological Science
Molecular Steps of DNA Replication
BIOL
114 Home
from Freeman's Biological Science
Molecular Steps of DNA Replication
 |
Replication starts by opening
of the DNA helix at a particular sequence called an origin of replication
(ori). In order to open and unwind the helix, a topoisomerase
enzyme is needed.
Bacteria, even during logarithmic growth, have ONE map position where DNA can originate replication. Eukaryotes have MANY origins of replication, all of which run concurrently. In either case, each origin of replication runs bidirectionally, with TWO replicating forks. |
To follow the step by step process, click the image:
Di-deoxy sequencing
