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BIOL 238 Microbiology
Office: Hig 302, Hours: M 1-3, TW 2-4
Spring Semester 2009
TR, 8:10, TOM 101
Microbiology is the study of organisms too small to be seen by the naked eye. The human body contains ten times as many microbial cells as its own; some microbes are considered an essential part of the human body.Other microbes inhabit environments that humans consider “extreme,” such as superheated deep-sea thermal vents, or salt-saturated soda lakes. BIOL 238 explores the cell biology, ecology, and medical applications of bacteria, archaea and eukaryotic microbes.

Syllabus for BIOL 238 Microbiology
Date
Topic
Response and Assignments Due
Jan
13
15
Microbes throughout history. PPT01
Microscopy: Seeing unseen life. FSU. PPT02
Ch. 1
Ch. 2; pp 2-3
Jan
20
22
Bacterial cell structure. Q1. Q2. PPT03A
Cytoskeleton and cell division. Salmonella.
PPT03B
Ch. 3; Ani: Replisome
Bowman Ani: Motility
Jan
27
29
Growth and life cycles Calculations. HiB vaccine. PPT04
Environmental factors. Quorum sensing. Oligotrophs. PPT05
Ch. 4; Ani: Endospore
Ch. 5
Feb
3
5
Viruses. PPT 06
Viral diseases. PPT 11
Ch. 6; Ani: Lysis
Ch. 11
; Ani: Influenza & HIV
Feb
10
11
12
Research: Quorum sensing. Test review.
Review: W 11:30-1:30 PRC L21

TEST 1
Smith

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Feb
17
19
Bacterial genomes. PPT 07
Gene expression.
PPT 08
Ch. 7; Ani: DNA replication
Ch. 8
; Ani: Protein Export
Feb
24
26
Gene transfer and regulation. PPT 09; PPT 10
Biofilms. 4:15 Dan Wozniak: PPT Seminar
Ch. 9
Ma; pp 345-372,
p 445 Fig.12.12
SPRING VACATION
Mar
17
19
Energy and catabolism. PPT 13
Electron transport. PPT 14
Ch. 13
Ch. 14; Ani: ETS & ATPase
Mar
24
26
Anabolism and Biosynthesis. PPT 15
Nitrogen Fixation (Jennifer Smith)
PPT N2 Fixation
Ch. 15; pp 594-602
Mar
Apr
31
2
Origins and evolution. PPT 17 Review 3:00-5:00 RBH 109
TEST 2
 Practice Pathways
Ch. 17
Apr
7
9
Bacterial diversity. PPT 17-18
Archaea.
PPT 19
Ch. 18; pp 1001-1006
Ch. 19
Apr
14
16
Eukaryotic microbes. PPT 20
Microbial ecology. PPT 21
Ch. 20; Wiki page
Ch. 21
Apr
21
23
Global environment. PPT 22
Human microflora and innate immunity. PPT 23
Ch. 22; Wiki comments
Ch. 23
Apr
28
30
Immune response. PPT 24
Microbial pathogenesis. PPT 25
Ch. 24; Ani: Activation
Ch. 25
REVIEW: May 4 & 7, 4:00pm-5:00pm, TOM206
TEST 3: May 4, 6:30 pm TOM206 or May 8, 8:30 am TOM101
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Prerequisite: BIOL 114

Deadlines: All reading response Emails and Wiki components listed on syllabus are due by 12:00 midnight BEFORE class date.
No exceptions or extensions. Note that Gmail and Yahoo often experience transmission delays; Kenyon email is safer.

Reading: Slonczewski & Foster (2008) Microbiology: A Genomic Approach (Norton, 1E). Either new book or full Ebook is acceptable. Animations are required.
All reading assignments are due 12:00 midnight before the date on the syllabus.

Attendance and participation. 100% attendance is expected, including the Departmental seminar listed on syllabus. Arrive on time, prepared to participate and make short presentations to class. Computer policy: You are welcome to bring PC, and use appropriate internet materials during class, while paying attention. Email is not allowed in class. Extra Credit: Add items for Microbial World News.

Chapter response. By midnight before class, email a response to the full chapter assigned. Email must include:

  • Ten thoughtful questions or comments. Cite page number for each. Comments may extend the material, "If Episculum cells are so large, how can their surface absorb enough nutrients?” or address clarity, “I don’t understand this specific point about . . . .” or indicate interest level, "I want to know more about . . . .”
  • Length of time it took you to read the chapter.
  • Difficulty of chapter, compared to texts of other 200-level biology courses

19 out of 22 chapter responses must be completed for an A grade. Each one less than 19 decreases the grade by one full letter (A, B, C, D, F). Only full chapters assigned may have responses. No late assignments accepted.

Tests. There are three tests, including Test 3 on the exam date.
.
Wiki Project. A MicrobeWiki page will be constructed on any topic of microbiology, approved by instructor. Start by copying class template into a page of your title. By April 14 the page should include approx. 3000 words and 3 or more figures. All components must include proper citation and permission. All deadlines refer to 12:00 midnight BEFORE class due.

Grades. Your grade is based 20% on each of three tests; 20% Wiki page; 10% class attendance; and 10% textbook responses papers.

Academic Honesty. All rules and standards stated in the Student Handbook apply.

Learning Disabilities. Consult the Coordinator of Disability Services for appropriate accommodations.