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BIOL 55 Genetic Analysis
Dr. Joan Slonczewski
Hig 322 Fall Semester, 9:40 TR, 1999
Texts assigned:
Human Molecular Genetics
by Tom Strachan and Andrew P. Read
HMG
Molecular Genetics of Bacteria (reserve in Hig 322)
by Larry Snyder and Wendy Champness
MGB
Population Genetics: A Concise Guide
by John H. Gillespie
PG
The History and Geography of Human Genes (reserve in Hig 322) 
by L. Luca Cavalli-Sforza, Paulo Menozzi, and Alberto Piazza
HGHG
Daughter of Elysium (copies loaned), by Joan Slonczewski
 
Articles provided in class
ART #
 
DATE  
SUBJECT
ASSIGNMENT
Aug
Sep
31
2
 Human pedigrees—Case study

Global regulation in bacteria

 HMG Ch 3 p 61-75; ART #1

MGB Ch 12 p 297-326
Sep
7
9
 Discuss articles

Organization of human genome

 ART #2

HMG Ch 7 p 147-175
Sep
13
16
 Mon. 1:10 Multigene families (Carol Park)

Discuss articles

 HMG Ch 8

ART #3
Sep
21
23
 Evolution of genomes

Gene structure Wilson lecture – 7:30

 HMG Ch 9 p 203-222

HMG Ch 9 p 223-238
Sep
28
30
 Genes in populations: Hardy-Weinberg

Genetic drift; computer simulation

 HMG Ch 3 p 76-81; PG Ch 1

PG Ch 2 p 19-35
Oct
5
7
 Mutation
TEST 1
 HMG Ch 10
Oct
12
14
October Break

Physical Mapping 

 HMG Ch 11, Web topic
Oct
19
2O
21
 Human Genome Project

Claire Fraser, HHMI Lecture – Wed. 7:30pm

Claire Fraser, Bio lecture – 4:15pm

 HMG Ch 13
Oct
26
28
 Plasmids—from bacteria to biotech

Discuss articles

 MGB Ch 4; ART #4
Nov
2
4
 Identifying disease genes

Discuss articles

 HMG Ch 14; ART #5
Nov
9
11
 Molecular pathology

Discuss articles

 HMG Ch 15; ART #6
Nov
16
18
 Review
TEST 2
  
   
Thanksgiving Break
  
Nov
Dec
30
2
 Quantitative genetics

Human gene frequencies

 PG Ch 5 p 103-123

HGHG p 11-30
Dec
7
9
 Genetic history of humanity

Science fiction discussion

 HGHG p 60-92, Web progress

Daughter of Elysium 
Dec
14
 Web Projects