BIOL 333
Environmental Toxicology
Spring Semester 2005

Tuesday & Thursday
Period B
(9:40 - 11:00 AM)

FSH 105

Reading Materials and sources:

Primary Literature and journalistic sources: Articles on the BIOL 333 e-res course page and handouts in class.

Scientific Text
: CH Walker, SP Hopkin, RM Sibly, and DB Peakall (2001) Principles of Ecotoxicology, 2nd edition (available at Kenyon bookstore)

Popular Press: T. Colburn, D. Dumanoski, and JP Myers (1996) Our Stolen Future
(available at Kenyon bookstore)

All reading assignments must be completed before the date indicated on the syllabus.

Policies and Expectations:

Class attendance: 100% attendance is expected, and absences will detract from one's grade. Please see me immediately about conflicts due to sports events, performances, etc.

Class participation: To participate fully in class, you must thoughtfully read the assigned material before each meeting. Intelligent, vocal participation in class will be the primary determinant of class participation grade. Please feel free to ask questions, add insights, correct the instructor's innacuracies, etc . at any time during class

Scheduling and Deadlines. Please plan carefully. Exam schedules and deadlines for submitting assigned work are firm, and extensions will not be granted for conflcits with the workload for other courses. Accomodations due to illness or other personal situation must be requested and negotiated through the Dean of Students or the Health and Counseling Center.

Academic Honesty. Do not lie, cheat, or plagiarize. Do your own work on exams. In writing projects, properly cite your sources of information, and acknowledge the help you receive from others. Kenyon's policy on academic honesty will be strictly observed. Explicit guidelines relating to projects or collaborative assignments will be discussed in class.

Special Needs. For assistance related to a physical, psychological or learning disability that may impact your ability to participate fully in the course, please speak with me and with Erin Salva, Coordinator of Disability Services (PBX5453; All information and documentation of disability is confidential.

Course Requirements and Grading Scheme:  
Class attendance, attitude, participation


Homework, response papers (multiple deadlines) 15%
Exam I (March 3) 20%
Exam II (April 21) 20%
Writing Project (multiple deadlines) 30%
Total 100%

**Updated January 12, 2005** 
Work Due
Course Introduction: philosophy, terminology, acronyms.
Video/response:  Frontline: Fooling with Nature

Walker Introduction, pp. XIII-X

20 Major Classes of Contaminants; Toxicology basics Walker Ch. 1, pp. 3-22;
NLM Toxicology Tutor I Introduction
Response Paper 1a
Why do this stuff? Risk analysis and public perception.

1-FACSNET: Reporting on Risk Assessment;
2-NLM Toxicology Tutor I: Risk Assessment; Exposure Standards and Guidelines
3-SETAC Technical Issue Paper
4-Reserve reading on e-res

27 Toxicity Testing I:  Dose responsiveness Walker Ch. 6, pp. 91-118;
NLM Toxicology Tutor I Dose and Dose Response
Toxicity Testing II Reserve reading on e-res
Response Paper 2
3 Organic Pollutants:  fate, transfer, bioaccumulation Colburn Ch. 6 (pp. 87-109) and Ch. 2 (pp. 23-28);
Walker Ch. 3 (pp. 33-45); Ch. 5 (pp. 78-90)
Organic Pollutants:  metabolism, disposition, toxicity

Walker Ch. 5 (pp. 59-78);
NLM Toxicology Tutor II: Toxicokinetics

10 WP in DC NIH DEV-1 Study Section
Endocrinology, Receptor pharmacology

Colburn, Ch 3, 4, 5 (pp. 29-86)
Reserve reading on e-res

Preliminary Project Proposal
17 Endocrine Disruptors I Reserve reading on e-res
Response Paper 3
Endocrine Disruptors II Reserve reading on e-res
Response Paper 4
24 Dioxin-like compounds and AH Receptor Reserve reading on e-res
Project: Annotated Bibiliography
Dioxin-like compounds Reserve reading on e-res
Response Paper 5
3 EXAM I .
Exam I post-mortem  
24 CYP1A and TCDD toxicity Reserve reading on e-res
Response Paper 6
Contaminant Mixtures and Toxic Equivalents

Walker Ch. 9, pp. 153-161
Reserve reading on e-res

31 No Class WP at University of Cincinnati
Abiotic factors affecting toxicity Reserve reading on e-res
Response Paper 7
Project: Outline
7 Introduction to Metals

Walker Ch. 4, pp. 46-58.
Reserve reading on e-res

Metals II Reserve reading on e-res
Response Paper 8
14 Population-level effects; evolution of resistance Walker Ch. 13, pp. 220-237
Reserve reading on e-res
Response Paper 9
Population-level effects II: costs of resistance Reserve reading on e-res

Response Paper 10
21 EXAM II .
Special Topic TBA

Reserve reading on e-res

28 Special Topic TBA Reserve reading on e-res
Completed Projects for Distribution
Project Review Panels Project for peer review

Fooling with Nature Reprise;
Final Comment;
Course Evaluation

Response Paper 1b
(in class)
May 9

Revised Projects Due 12:00 Noon
(this is a Monday)



[Kenyon Biology Home Page]
[Kenyon College Home Page]