|
Dr.
Wade Powell
Office: FSH 202 Lab: FSH 204 PBX: 5396 powellw[a]kenyon.edu Scheduled Office hours: M/4-5; W/1-3; R/2-4 |
BIOL
333
Environmental Toxicology |
Spring
Semester 2005
Tuesday
& Thursday |
 |
Primary Literature and journalistic
sources: Articles on the BIOL
333 e-res course page and handouts in class.
Scientific Text: CH Walker, SP Hopkin, RM Sibly, and DB Peakall (2001)
Principles of Ecotoxicology, 2nd edition (available at Kenyon bookstore)
Popular Press: T. Colburn, D. Dumanoski, and JP Myers (1996) Our
Stolen Future (available
at Kenyon bookstore)
All reading assignments must be completed before the date indicated on the
syllabus.
Policies and Expectations:
Class attendance: 100% attendance is expected, and absences will
detract from one's grade. Please see me immediately about conflicts due
to sports events, performances, etc.
Class participation: To
participate fully in class, you must thoughtfully read the assigned material
before each meeting. Intelligent, vocal participation in class will be the
primary determinant of class participation grade. Please feel free to ask questions,
add insights, correct the instructor's innacuracies, etc . at any time during
class
Scheduling and Deadlines. Please plan carefully. Exam schedules and
deadlines for submitting assigned work are firm, and extensions will not
be granted for conflcits with the workload for other courses. Accomodations
due to illness or other personal situation must be requested and negotiated
through the Dean of Students or the Health and Counseling Center.
Academic Honesty. Do not lie, cheat, or plagiarize. Do your own work
on exams. In writing projects, properly cite your sources of information, and acknowledge the
help you receive from others. Kenyon's policy on academic honesty will be
strictly observed.
Explicit guidelines relating to projects or collaborative assignments will
be discussed in class.
Special Needs. For assistance related to a physical, psychological
or learning disability that may impact your ability to participate fully
in the course, please speak with me and with Erin Salva, Coordinator of
Disability Services (PBX5453; salvae@kenyon.edu).
All information and documentation of disability is confidential.
| Course Requirements and Grading Scheme: | |
| Class attendance, attitude, participation |
15% |
| Homework, response papers (multiple deadlines) | 15% |
| Exam I (March 3) | 20% |
| Exam II (April 21) | 20% |
| Writing Project (multiple deadlines) | 30% |
| Total | 100% |
|
Date
|
|
Topic
|
Reading
|
Work
Due
|
|||
| Jan |
18
|
Course
Introduction: philosophy, terminology, acronyms. Video/response: Frontline: Fooling with Nature |
Walker Introduction, pp. XIII-X |
.
|
|||
| 20 | Major Classes of Contaminants; Toxicology basics | Walker Ch. 1, pp. 3-22; NLM Toxicology Tutor I Introduction |
Response
Paper 1a
|
||||
| Jan |
25
|
Why do this stuff? Risk analysis and public perception. |
1-FACSNET: Reporting on Risk Assessment; |
.
|
|||
| 27 | Toxicity Testing I: Dose responsiveness | Walker Ch. 6, pp. 91-118; NLM Toxicology Tutor I Dose and Dose Response |
.
|
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| Feb |
1
|
Toxicity Testing II | Reserve reading on e-res |
Response Paper 2
|
|||
| 3 | Organic Pollutants: fate, transfer, bioaccumulation | Colburn Ch. 6 (pp. 87-109) and Ch. 2 (pp. 23-28); Walker Ch. 3 (pp. 33-45); Ch. 5 (pp. 78-90) |
|||||
| Feb |
8
|
Organic Pollutants: metabolism, disposition, toxicity |
Walker Ch. 5 (pp. 59-78); |
.
|
|||
| 10 | WP in DC | NIH DEV-1 Study Section |
.
|
||||
| Feb |
15
|
Endocrinology, Receptor pharmacology |
Colburn, Ch 3, 4, 5 (pp. 29-86) |
Preliminary Project Proposal
|
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| 17 | Endocrine Disruptors I | Reserve reading on e-res |
Response Paper 3
|
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| Feb |
22
|
Endocrine Disruptors II | Reserve reading on e-res |
Response Paper 4
|
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| 24 | Dioxin-like compounds and AH Receptor | Reserve reading on e-res |
Project: Annotated Bibiliography
|
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| Mar |
1
|
Dioxin-like compounds | Reserve reading on e-res |
Response
Paper 5
|
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| 3 | EXAM I | . |
.
|
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|
SPRING
BREAK!!!
|
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| Mar |
22
|
Exam I post-mortem |
.
|
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| 24 | CYP1A and TCDD toxicity | Reserve reading on e-res |
Response
Paper 6
|
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| Mar |
29
|
Contaminant Mixtures and Toxic Equivalents |
Walker Ch. 9, pp. 153-161 |
.
|
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| 31 | No Class | WP at University of Cincinnati | |||||
| Apr |
5
|
Abiotic factors affecting toxicity | Reserve reading on e-res |
Response Paper 7 Project: Outline |
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| 7 | Introduction to Metals | Walker Ch. 4, pp. 46-58. |
.
|
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| Apr |
12
|
Metals II | Reserve reading on e-res |
Response Paper 8
|
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| 14 | Population-level effects; evolution of resistance | Walker Ch. 13, pp. 220-237 Reserve reading on e-res |
Response Paper 9
|
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| April |
19
|
Population-level effects II: costs of resistance | Reserve
reading on e-res |
Response Paper 10
|
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| 21 | EXAM II | . |
.
|
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| April |
26
|
Special Topic TBA |
.
|
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| 28 | Special Topic TBA | Reserve reading on e-res |
Completed Projects for Distribution
|
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| May |
3
|
Project Review Panels | Project for peer review |
.
|
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| 5 |
Fooling with Nature Reprise; |
. |
Response Paper 1b
(in class) |
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| May | 9 |
Revised Projects
Due 12:00 Noon |
.
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