Office: HIG 302 |
Fall 2010
Fridays 1:10-4:00, FSH 205 |
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Resources: PLOS Pathogens; J. Virology; Virology J. |
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AUG | 27 |
What are viruses? Suttle The Mimivirus: Is it a "cell"? Compare Iridovirus |
S&F Ch. 6; Mim1, Mim2 | |
AUG SEP |
31 3 |
Reading: Poliovirus replication Poliovirus.
Smithsonian; FDR and Polio; ARF
movie. FRAP. Green
Pigs. Aequorea. Pull-down
assay. |
S&F Ch.11 (pp 393-398) Mueller; Belov |
3 questions |
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7 10 |
Viral
Biorealm Template
Page |
Vaccine handout |
Start Wiki Wiki Complete |
SEP | 15 17 |
Reading: Immunity--Innate versus Adaptive The Adaptive Immune Response. |
S&F Ch. 24 |
3 questions |
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22
24 |
Reading: Influenza Virus.
Animation. |
Ch. 11 (pp 399-405)
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3 questions |
OCT
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29
1 |
Reading: Influenza evolution since 1918. Accident? Translation and virulence. Initiation factors. |
Burgui; Zamarin | Individual Conferences: Paper Topic |
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8 |
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13
15 |
Reading: Herpes virus replication. Herpes viruses. Animation. Nuclear lamina |
Conferences: Paper Progress |
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19
22 |
Reading: Nonspecific host defenses. JAK-STAT Cytomegalovirus and birth defects. |
CDC; Luo, 2010 Fortunato, 2010 |
3 questions |
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26
29 |
Reading: HIV and AIDS NYT
History |
Ch. 11 (pp 405-415); Levy 1 Levy Ch. 2 |
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NOV |
3 5 |
Reading: HIV pathogenesis and antiviral therapy. |
Levy Ch. 13 Levy Ch. 14 |
3 questions
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10 11 12 |
Reading: Retroviral host factors |
Paper Draft 1 |
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17
19 |
Reading: Adenoviral gene therapy: Adenovirus
E1A; Hemophilia
Clotting
cascade. |
Tumor
Viruses; Nindl |
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NOVEMBER BREAK | |
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NOV DEC |
30
3 |
Student readings 1:10 TOM 206 Computer Viruses (Ron Griggs) |
TBA Computer Viruses; TBA |
3 questions |
DEC | 7 10 |
Student readings |
TBA TBA |
Final
Paper |
INTRODUCTION. Virology, the form and function of viruses, is a field of growing importance for human and veterinary health, agriculture, and global ecology. For this advanced seminar, we select major viruses and explore their means of propagation within cells, as well as their immunology and epidemiology. We consider the role of viruses in ecology, particularly global carbon cycles. Required reading: Assignments. Attendance. Viral Biorealm page. Each student authors a page using the Virus template, about an unusual or lesser known virus, preferably one infecting plants or non-human animals. Research Paper. Topic of student's choice, in consultation with instructor. Must address a current research question. Text minimum: 2000 words (Draft 1), 3000 words (Final), in addition to figures/legends/references.
Standards for Projects and Exams. The standard College guidelines on individual authorship and plagiarism apply to all work, as stated in the Student Handbook 10-11. All projects, including html, must include footnotes and references cited in detail comparable to that of a term paper. Each exam must represent the work of one individual student. Disabilities. If you have a physical, psychological, medical or learning disability that may affect your ability to carry out assigned course work, please contact the Office of Disability Services at 5453. The Coordinator of Disability Services, Erin Salva, will review your concerns and determine, with you, what accommodations are appropriate. All information and documentation of disability is confidential. |